DYSPEPSIA GENERATION

The Foundry.

At least four Muslim members of the Texas Republican Party shared their experience at the state’s Republican convention over remarks they described as Islamophobic.

Nobody worries about ‘Nazi-phobic’ or ‘Communist-phobic’, so why the uproar about ‘Islamophobic’? A phobia is an irrational fear, and a fear of Islam, like a fear of Nazis or a fear of Communists, is entirely rational, as history plainly demonstrates.

“When they say Sharia-free, that means Muslim-free, no practices of Islam,” Mohamed Hussein, an attendee, told The Texas Tribune. “No one is calling for the state to implement Sharia laws.”

Of course not—Muslims know that would not be well received (although they do it in Europe, and I suspect it’s only a matter of time and increased Muslim population growth before it happens here). What ‘sharia-free’ means is the elimination of the stealthy growtho of sharia-law in parallel with normal American law, as is currently happening in the UK. Muslims set up their own sharia-law tribunals and pressure all Muslims to use them in place of the existing legal structure. (Orthodox Jews have done the same thing; it’s not unusual for tribal peoples living in non-tribal societies.)

Hussein said he was in disbelief that he was told to convert or leave—for the first time in his life.

But that’s exactly the choice that Islam gives to non-Muslims. Convert or go away (Actually, historically it was convert or die, but they can’t get away with that in the modern world). If you’re a Christian or a Jew, you get a third choice: Become a dhimmi, which is kind of like being a Negro in the Democrat South.

The New Neo.

Yes, we already knew some of what is revealed in the recent report issued by British MP Rupert Lowe on the so-called “rape gangs” that exploited British girls for decades. To illustrate, note that I wrote my first post on the subject in 2015, and in it I quoted this:

The sex-trafficking ring in Rotherham may well be the worst in the West ever, or so one would hope. British officials have now identified at least three hundred suspects in a crime syndicate that raped and trafficked underage British girls for years, while local police ignored signs and clues for years…

It was already known that the perps were almost exclusively what the Brits call “Asian men” – in this case, Pakistani – and the victims were underage white girls, mostly poor and often neglected. So, what’s new?

Cutting their own throats slowly….

Muslims inevitably see non-Muslims as prey.

The Foundry.

The Trump administration has struck another blow against DEI, this time issuing a lawsuit against a “first of its kind” racial reparations program in Illinois.

In 2019, the city of Evanston, Illinois, approved a “Local Reparations Restorative Housing Program” that was set to hand out tens of millions of dollars to residents—or the descendants of residents—who had allegedly been discriminated against.

What’s notable, and suable, about the Evanston reparations program is that the awardees of cash payments from the city government didn’t have to prove that harm was caused to them or their ancestors.

Instead, eligible recipients have been limited to black adults who lived in the city between 1919 and 1969, along with their children, grandchildren, or great-grandchildren.

The Department of Justice noted that the “city has not identified any specific acts of discrimination that violated the constitution or a statute that these payments are intended to remedy.”

The program went into effect in 2021, the height of the Great Awokening, and has distributed a considerable amount of money.

The way to stop discrimination on the basis of race is to stop discriminating on the basis of race.

Not the Bee.

The line between reality and satire gets thinner by the day.

If you didn’t hear, the fake news has gone all-out this past week with actual journalism (albeit stupid journalism) into the algae bloom that has hit Trump’s renovated Reflecting Pool on the National Mall.

It’s funny that they didn’t have time to analyze the water when it was dark green during Obama’s years, or to pay attention to billions in migrant fraud, or to investigate Covid lies, but they did have time to send a crew to get water samples to make Trump look bad.

Read it.

A new treatment that blocks an aging-related protein restored lost cartilage in old mice and helped prevent arthritis after knee injuries. Human cartilage samples showed similar signs of regeneration, raising hopes for a future drug that could repair joints instead of replacing them.

“We Were LIED To About America…”

The Media Lied, America Was NOTHING Like We Thought

America How is this NORMAL

Brit STUNNED at “They Refused to Play the US National Anthem, So They SANG it!”

The World Cup Proves Europe Was Wrong About America

The World Cup Is Proving America Was Right

Do World Cup Tourists Love America More Than We Do?

Everything We Thought About The USA Was Wrong…

European World Cup Tourists SHOCKED After Finding Out THEY HAVE BEEN LIED To About America!

World Cup showed the REAL America

Europeans FINALLY See The REAL America!

Brits SHOCKED by Texas Football Culture

… and, from the people who don’t have the Second Amendment:

Europeans React To Can USA Survive A Full Scale INVASION! l Why It’s Impossible? (CIVILIANS in the U.S. have more guns than all of the European armies put together … including Russia.

Trump Does Not Understand the War He Lost (Tom Nichols/The Atlantic)  The war isn’t really over, of course, but mind-readers in the Narrative Media KNOW that he lost and KNOW that he doesn’t understand anything anywhere anytime.

CNN Spins Local Newsom Investigation as Trumpist Political Witch Hunt Because what else could it POSSIBLY be?

ABC Downplays Illegal Alien Ramming Car into ICE Agent as ‘Suspect’

Former Judge’s ICE Obstruction Conviction Upheld

Iran Found Trump’s Bone Spur (Bret Stephens/New York Times)

Trump’s Iran Nuclear Deal Risks Falling Short of Obama Version (Jonathan Tirone/Bloomberg)

More Than 770,000 Children Are No Longer Receiving SNAP Benefits After Trump Changes Federal Food Program (Nicole Santa Cruz/ProPublica)  Because, as we all know, providing food for children is TOTALLY the respoosibility of the Federal government—and the Federal taxpayer.

After draping White House in gold, Trump heads to ‘the real deal’: Versailles (Washington Post

Elon Musk’s Race War Just Took Darker Turn–Time for a Global Response (New Republic)

MAGA hawk mutiny deepens Trump’s isolation on Iran (Zachary Basu/Axios)  MAGA is the New Nigger.

Vance’s slick answers on ‘The View’ can’t hide his biggest problem for 2028 (Paul Waldman/MS NOW) He cant avoid TRUMP COOTIES.

Death rate in ICE immigrant detention centers more than doubles under Trump, Reuters analysis finds (Reuters)

Trump plan would fence park near White House long used by tourists, protesters (Dan Diamond/Washington Post)

Klepper Implies Trump Wanted German Chancellor To Get Him a Nazi Jersey

The Real Trump Resistance Doesn’t Need a Hashtag (New York Times)

Trump in Defeat — The president went to war triumphant and will likely leave greatly weakened. (Jonathan Lemire/The Atlantic)

The Next Step in Criminalizing ICE Protests Is Here (Spencer Ackerman/FOREVER WARS)

Rick Jackson’s Georgia win is an embarrassing blemish on Trump’s record (Politico)

The De-Trumpification Process Begins Now (Brian Beutler/Off Message)

GOP senator: Trump Iran deal ‘tremendous foreign policy blunder’ (Max Rego/The Hill)

O’Donnell Seeks Warnock’s ‘Spiritual Guidance’ Over UFC Fighter’s Michelle Obama Insult

Read it.

Only 1% of the American population identifies as vegan (a person who refrains from using or consuming any animal products), and around 3% of the population identifies as vegetarian. It is therefore a little confusing as to why American political and social discourse is hijacked by vegan issues so often.

Leftist activists have adopted the age-old mantra that the “squeaky wheel gets the oil”; but imagine a wheel that never gets enough oil? Imagine a movement specifically designed to keep society constantly on egg shells, trying to figure out different ways to satisfy that squeaky wheel so it will finally shut up?

One eventually has to ask the obvious question: Why don’t we simply throw that insufferable wheel in the garbage?

A perfect example of why Americans need to start aggressively discriminating against veganism as a movement has popped up in Oregon. A new initiative called the PEACE Act (IP28) has enough backing to make it on the state ballot in November. The initiative originally gained support as a way to “end animal cruelty”, but the details of the proposed law turned out to be a vegan’s version of Orwell.

Read it.

German director Uwe Boll’s latest film about a man who turns to vigilantism after becoming frustrated by rising street crime has been effectively barred from release in Germany. According to Boll, the ban is linked to the film’s portrayal of migrants as perpetrators of serious crimes.

Citizen Vigilante, starring former Hollywood actor Armie Hammer, has been in effect barred from release in Germany after the country’s film classification board refused to grant it any age rating.

The action thriller, due to debut in North America on June 19, stars Hammer as Sanders, a man whose violent campaign against criminals transforms him into a social media sensation.

Thank God we have the First Amendment—unlike fascist Europe.

Read it.

French activist and online commentator Thaïs d’Escufon says she could face prison for saying immigration is the number one threat to French women. In an X video posted on her page, she argues that her case demonstrates the shrinking space for free expression in France.

The case stems from statements she made on BFM TV in 2023, during a discussion about a rape involving an illegal immigrant. d’Escufon, who was herself the victim of a home invasion and sexual assault two years earlier at the hands of a Tunisian migrant, said during the segment that “The main danger for women is immigrant men, Africans, blacks, and Arabs.”

DILCRAH (the Interministerial Delegation to Fight Against Racism, Antisemitism, and Anti-LGBT Hate) filed a complaint after that TV appearance, leading to prosecution.

Read it.

A privately funded inquiry organised by Rupert Lowe’s Restore Britain party has accused British authorities of allowing organised child sexual exploitation networks to operate across the country for decades, claiming that political sensitivities repeatedly took precedence over protecting vulnerable girls.

The 219-page Rape Gang Inquiry Report is not an official government investigation and did not possess statutory powers to compel witnesses or evidence. Instead, it draws on survivor testimony, whistleblower accounts, court records, previous inquiries, and expert evidence gathered during hearings organised by Restore Britain.

The report examines Britain’s rape gang scandal, a series of cases uncovered in towns and cities across England in which groups of men, largely of Pakistani Muslim heritage, sexually exploited underage girls, often over many years. Previous official investigations in places including Rotherham, Rochdale, Oxford, and Telford found repeated failures by police, social services, schools, and local authorities to intervene despite numerous warnings.

ATQUE: UK – the Grooming Gangs

ATQUE: RAPE GANGS: New Report Exposes How Woke Ideology Enabled One of the Most Horrific Scandals in British History

Read it.

An Eritrean rapist avoided deportation from Sweden because he is “integrated” there, and the rape he committed was described by a court as “brief” and “without threats or blows,” according to a court.

The offender, a care worker in his 30s, was sentenced to four years imprisonment for raping an 82-year-old woman. His victim—who previously received home care services from the now convicted criminal—suffers from impaired memory, but was able to recall her ordeal on the night of November 3rd, 2025, Samnytt reports.

The victim’s son contacted the police alleging an incident had taken place. After various convoluted attempts at an alibi contradicted by DNA evidence, the Eritrean was convicted.

Slowly cutting their own throats….

Read it.

Official figures show that 710 migrants crossed the English Channel on eleven ‘small boats’ on Monday, June 15th.

With the single largest number to make the crossing in a single day this year, it’s clear that government actions are having little to no effect. For instance, to date the ‘one-in, one-out’ deportations to France policy shows no signs of acting as a deterrent.

Instead the main brake on illegal activity comes from inclement weather. This, including recent high winds at sea, meant six days with no crossings. Yet as conditions improved, Monday saw illegal ‘small boat’ migrants—what Reform UK leader Nigel Farage calls fighting-age men who have thrown away their travel documents—rock up on England’s shores in the largest daily total of the year so far.

Slowly cutting their own throats….

Read it.

As riots triggered by migrant attacks convulse the UK, the debate over immigration in Europe is reaching a fever pitch. The same question is asked, time and again: If nobody voted for this, why does it keep on happening? In the past two years, migrant violence has been recorded—and in some cases triggered violent public backlash—in Germany (a toddler and man stabbed to death by an Afghan); Belfast (a man stabbed in the street by a Sudanese refugee); France (a deadly stabbing by an Algerian in Mulhouse); as well as Poland, Sweden, and Spain, among others.

By contrast, the steep rise in anti-Christian hate crimes, meticulously tracked by the Observatory on Intolerance and Discrimination Against Christians in Europe, has gone largely unreported. In May alone, OIDAC Europe reported 37 hate crimes targeting “Christian places of worship, religious symbols, religious spaces, Christian institutions, and Christian individuals,” including:

• 13 arson-related attacks (the highest in 2026 thus far)
• 10 cases of vandalism
• 3 cases of deliberate “desecration”
• 3 cases of physical violence
• 3 thefts of religious objects
• 3 cases of “vandalism and violence”
• 1 case of incitement
• 1 case of disruption of worship

No surprises here.

Not the Bee.

The way to stop discrimination by race is to stop discriminating by race.

Read it.

This is why I no longer use Chrome.

Read it.

She is,  of course, a Woman of Color.,

Read it.

Police in Toronto announced on Tuesday that they believe young adults are being hired and paid online to shoot at local synagogues.

The announcement follows a string of arrests in connection with shootings at a range of targets in the Canadian city, including multiple synagogues.

“What we know is bad actors are using criminal elements in our city to carry out these dangerous incidents,” Toronto Police Service Chief Myron Demkiw said at a press conference. “It is clear that some of the people hiring these criminals want to create a sense of fear in our communities, including the Jewish community.”

Demkiw said the suspects were being recruited through online networks and offered payments if they filmed themselves engaging in the shootings.

“Who’s paying for this?” he asked. “This is what we are trying to determine.”

I suspect that at least one of them is named “Mohammed”.

Not the Bee.

Man, Texas REALLY knows how to do “toxic” masculinity.

The risks of rescuing those people were huge.

Yet those men didn’t hesitate. Not even for one moment.

Watch it.

You have been warned.

My wife and I were caught in Texas 2021 Frozen February. We now have a gas-powered backup generator.

The Register.

Imagine being paralyzed so badly that not only can’t you move your hands or feet, but you can’t speak either. For years, brain computer interfaces have presented the tantalizing promise of reading brainwaves well enough to allow a person to communicate and access a PC.

Now, a new breakthrough shows how someone can talk and even work a job while afflicted with a motion-robbing disease.

A team of scientists from the University of California, Davis, published a paper Monday detailing a years-long study of a brain computer interface (BCI) system implanted in a patient with amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig’s disease), which destroys motor neurons and causes loss of motor control and eventual paralysis. According to the team, their patient, Casey Harrell, has been living with BCI implants since 2023 that are still working today, giving him the ability not only to control a computer cursor with his thoughts, but also to speak.

Read it.

Advances in materials and science are pushing optical cooling out of the lab and closer to actual semiconductors and other electronic systems. “The ability to diffuse energy in a highly targeted way has profound ramifications that extend from performance and costs to sustainability,” Pauzauskie said.

In fact, the appeal of optical cooling extends beyond chips. The technology could also enable more precise scientific instruments: atomic clocks, telescopes, satellites, and more, said Alexander Albrecht, a research assistant professor at the University of New Mexico. “It’s possible to cool exactly where you generate heat—down to microscopic ‘hot spots’—rather than cooling an entire enclosure.”

Read it.

Inside every living cell, tens of thousands of different types of proteins are at work: ferrying molecular cargo, relaying signals, repairing DNA, deciding whether a cell should divide or die. Most of these proteins are too small to image with existing microscopes. Those that can be imaged must be pulled out of the cell and studied in isolation — not in the crowded, dynamic environments that drive the processes of life.

That is about to change. In three papers, researchers at Biohub and UC Berkeley report successful results from a technology called a laser phase plate, which uses a laser 100 million times brighter than the Sun to significantly improve the contrast of images produced by cryo-electron microscopy (cryo-EM). The laser phase plate could make otherwise faint, blurry proteins inside intact cells visible, including many proteins most relevant to human disease.

“Rough estimates suggest that scientists can image 10% of the human proteome in purified form using existing cryo-EM — and fewer than 1% of proteins in their native cellular environment,” says Scott Fraser, president of dynamic imaging at Biohub. Scientists believe the laser phase plate could make more than 50% of the proteins that carry out cellular functions visible.

“This is just the first step,” says Bridget Carragher, founding technical director of imaging at Biohub. “It’s like seeing first light through a telescope. The science it enables — that comes next.”

CNN, a Voice of the Crust.

Bear in mind that this is CNN, so you’ll want to read the agreement and skip the tendentious commentary.

Read it.

A North Carolina school district agreed Monday to pay $95,000 to settle a student’s lawsuit after her school painted over her tribute to Turning Point USA founder Charlie Kirk shortly after his assassination.

A high school junior at Ardrey Kell High School secured permission to paint “Freedom 1776” and “Live Like Kirk—John 11:25” on the school’s “spirit rock,” a large boulder that often features messages on political topics. Yet, within hours, she learned from social media that officials had ordered the “Live Like Kirk” portion painted over.

The Charlotte-Mecklenburg Board of Education agreed to adopt a new student speech policy, issue a public statement exonerating the student, and pay $95,000 in damages and attorneys’ fees, Alliance Defending Freedom, which represented the student, announced Monday.

Read it.

Figures released from German police statistics show that Syrian nationals were the largest foreign-national group among suspects identified in violent incidents and certain sexual offences recorded at public bathing sites last year.

The data, obtained by Junge Freiheit from a federal government response to a parliamentary question, showed that authorities recorded 360 violent incidents at public swimming and bathing areas in 2025 involving 426 suspects. Of those, 178 did not hold German citizenship.

Among foreign-national suspects, Syrians accounted for the largest group, with 52 suspects identified in connection with violent offences. Afghan nationals were the second-largest group with 15 suspects, followed by Turkish nationals with 11.

The figures have attracted renewed attention amid ongoing debate in Germany over migration, public security, and the integration of recent arrivals.

The issue has remained in the spotlight following a series of high-profile violent crimes and knife attacks in Germany and neighbouring Austri

The Antiplanner.

In 2014, a 13-mile extension to Minneapolis’ Blue light-rail line was projected to cost $1.0 billion and open for business in 2020. The latest word is that it is going to cost more than $3.5 billion and won’t begin operating until 2032.

Minneapolis is, of course, run by Democrats.

The line is a northern extension of the region’s first light-rail line, which connected downtown Minneapolis with Bloomington. That line was sold to the public based on claims that it would relieve congestion, but it actually made congestion worse. As reported in the Minneapolis Star-Tribune, the light-rail line was given priority at traffic lights. Because those lights were coordinated with traffic lights on the para

lel Hiawatha Avenue, the trains interfered with signal coordination on the avenue, a major north-south route in the city.
Engineers tried to fix it but gave up. Moreover, state Representative Phil Krinkie uncovered documents showing that the state knew all along that the light-rail line would make congestion worse, and ignored the problem because “transit had to have an advantage” over driving.

This is why you don’t have rail lines sharing ground level street space. Dallas has the same problem.

Not the Bee.

I’m sorry, but I can’t help but laugh at the “Radical Queer Feminist” sign in front of the waving Palestinian flag.

Or maybe that ought to be “Palestinian fag”.

Read it.

A British appeals court ruled Monday that the government acted lawfully in banning a prominent pro-Palestinian group as a terrorist organization.

Jewish groups welcomed the decision to maintain the ban on Palestine Action, which has staged multiple destructive attacks on military installations and weapons manufacturers in Britain.

The government banned Palestine Action in July 2025 after some of its members broke into an air force base and damaged two military aircraft as part of a protest against the U.K.’s relationship to Israel during the war in Gaza. The ruling meant that anyone displaying support for the group has been subject to arrest and imprisonment.

The British High Court declared the ban unlawful in February, concluding that the ban interfered with Palestine Action members’ rights to speech and assembly. Now, a five-judge U.K. Court of Appeal panel has ruled that the group’s activities met the legal standards for terrorism and the government’s decision to ban the group was justified and proportionate.

Read it.

The difference is coverage. A hijab covers the hair, ears, and neck while leaving the face visible. A niqab covers the face except for the eyes and is usually worn with a headscarf and a loose robe. A burqa covers the whole body and the entire face, with a mesh screen or grille over the eyes so the wearer can see out.

The terms are often confused, but they are not interchangeable. All three are forms of Islamic modest dress worn by some Muslim women, shaped by region, religious interpretation, family tradition, and personal choice. The hijab is by far the most common worldwide. The niqab is worn by a smaller number of women, often in Gulf Arab countries and parts of South Asia. The full burqa is most associated with Afghanistan. The distinction matters because news coverage and political debate often use the words loosely.

Babylon Bee.

I like the gorilla goalie. That would add some spice.

Watch it.

The YouTube channel From Down Under to Down South. I find stuff like this fascinating.

Watch it.

I suspect that the transition from a strong blade with a single edge to a weaker blade with a double edge would be quite confusing.

I would also like to see how he does with a basket-hilted curved cavalry sabre, which ought to be closer to what he’s used to.

Abby Zinman, a Typical Modern Woke Female writer for Buzzfeed (Voice of the Wokerati) illustrates why we have a population deficit and why men aren’t asking women out any more. (“Where are all the good men?” “Back in your twenties where you left them.”)

I’d say read it for entertainment, but it is far from entertaining. It is, however, informative, in a gotta-shake-your-head kind of way.

The self-absorption and entitlement are strong in this one.

And, of course, the men involved are SOLELY to blame. (Girl, if all the men you date have problems, maybe they aren’t the problem.)

Read it.

Peptides are amino acids that are used to issue instructions to the body’s various systems. Ozempic, Mounjaro and Retatrutide are all peptides. These GLP-1s have a ridiculous number of things they do in terms of measurable results of reduction: cancer rates, strokes, heart attacks, diabetes, obesity, even aging. Some countries are considering making GLP-1s available to all (not just the obese or diabetic) because of these benefits.

There are a host of other things that “biohackers” are injecting. I am posting this here because I think anyone with knee or joint pain would do well to check out BPC-157. I have personal knowledge of people who have cured chronic knee pain with 1-3 injections of the peptide. Old muscle pain? Totally fixable with a trivial injection.

Any search on X will show a host of other peptides in the market, offering or suggesting help for a huge range of maladies. Memory loss? Check. Big drug companies are working on peptides for cancers. Some peptides give you a tan, others are key ingredients in skin rejuvenation (potentially making the Botox world a dead end in human anti-aging treatments). There are peptides in development to cure myopia, and even regrow the optic nerve! Things that we knew could not be done are being done. The peptides can tell the body to do something in old age that it usually would only do at a much earlier (or even foetal) stage of development.

None of the non-GLP-1 peptides (as far as I know) is FDA-approved. Most of them probably never will be, because there is no financial incentive to jump through the hoops for something that cannot be patented and which can be purchased inexpensively.

Government is why we can’t have nice things.

Read it.

New findings, published today (10 June) in Nature, help to answer the riddle of how vertebrates evolved the diverse array of brain cells that distinguishes them from other animals. It appears that a dramatic expansion of the genetic toolkit more than 450 million years ago enabled the emergence of different kinds of brain cells. These cellular innovations are shared across vertebrates – from primitive fish to mammals – and form the basis of the sophisticated brains seen today.

By comparing the gene activity of single brain cells across five species, including humans, mice, lizards, lampreys (a primitive, eel-like fish) and amphioxus (one of our closest invertebrate relatives), the team reconstructed how brain cell types evolved over deep time. They found that many of the major cell type families in vertebrate brains arose after a genome duplication event in the common ancestor of vertebrates roughly 520 million years ago. A further genome duplication (around 500 million years ago) then added to this.

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What they found was that if an injury occurs at a particular point in the branched structure of the antler, it makes a small callus and heals; the rack will be shed as normal, and next year, a new rack will grow, with an ectopic tine (branch) at the location where the damage occurred in the previous year. This is one of my favorite examples when I teach developmental biology students, on the topic of “here are some things not in your developmental biology textbook”. Using the tools we normally use in the field – chemical gradients, gene-regulatory networks, molecular pathways – try to come up with a model of how the point of damage is sensed at one location of a complex structure, then the whole thing falls off, and the memory is somehow kept – where – in the growth plate on the scalp? And then months later, a new structure appears, with a pattern dictated not just by the emergent result of genetically-encoded protein production (hard enough to explain) but also by the previous physiological experience of cells that are no longer here, which tells bone growth dynamics to take an extra turn and grow out in a very specific place. The effect disappears after a few years and they go back to normal.

Trofim Denisovich, call your office.

Read it.

The job of a tumor suppressor protein is right in the name: stopping us from getting cancer at the cellular level. But when they’re not working properly, the cell is left with limited defenses.

In a new paper published today in the journal Nature titled “Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding,“ researchers at the Innovative Genomics Institute (IGI) at UC Berkeley, UC San Francisco, and Gladstone Institutes, along with collaborators at University of Utah and Utah State University, report that a creative new CRISPR-based approach can selectively destroy cells carrying a mutation in a tumor suppressor found in nearly half of all cancers and up to 70–90% of cases of some of the most difficult-to-treat cancers, including ovarian, pancreatic, and non-small cell lung cancer.

“Not only can this approach target the ‘undruggable’ cancers that we know, we can also easily and quickly adapt this to new mutations,” says IGI Founder Jennifer Doudna, a co-author on the paper. “This is an exciting development for cancer therapies, and potentially for other applications as well.”

Read it.

In Chapter 10 (“Why the Worst Get on Top”) of The Road to Serfdom, F. A. Hayek argued that centralized political authority tends to elevate the worst people in society. Goons and demagogues do not rise to the top in totalitarian systems by accident. The logic of totalitarianism selects for thuggish leaders.

A less dramatic, but equally perverse, logic governs American academia.

The incentive structure of the modern American university encourages relatively unsuccessful scholars, those who fail to establish fruitful research programs early in their careers, to pursue administrative positions, where they wield authority over more successful colleagues, who actually generate educational value. As a result, the American university is disproportionately governed by relative academic failures.

An effective scholar enjoys benefits impossible to find elsewhere in today’s workforce: freedom to follow ideas wherever they might lead and a considerable amount of free time to do it. Those who succeed aren’t inclined to leave the laboratory or library for administration.

Though administrative salaries tend to be higher, the rest of an administrator’s work-life is poorer in every other respect, involving endless committee meetings, paperwork, budgetary knife fights, student and parent grievance adjudication, and the difficult business of cultivating donors. Intellectual freedom and scholarly prestige are nowhere in evidence.

Quanta.

In the first episode of the new season of ‘The Joy of Why,’ Nobel Laureate Jennifer Doudna discusses how she discovered CRISPR’s genome-editing power, the breakthroughs and hurdles during its explosive growth, and what lies ahead for this groundbreaking technology.

One of the most surprising and remarkable discoveries in recent scientific history has been CRISPR. Short for Clustered Regularly Interspaced Short Palindromic Repeats, CRISPR is a form of immune system that evolved in bacteria more than a billion years ago to defend against persistent viral threats. Under attack, bacteria can snip a small fragment of a virus’s DNA, store it in the CRISPR region of their genome, and then use it to recognize and destroy the same virus if it returns. The CRISPR-Cas9 system, to give it its longer name, consists of a short strand of guide RNA that identifies where to cut the DNA and a protein that acts as the molecular scissors.

What made this system truly revolutionary was the demonstration in 2012 that it could be reprogrammed with different pieces of guide RNA to edit virtually any genome in any species, and at a level of precision and ease that far surpassed existing gene-editing tools. Since then, the editing capability of CRISPR has been tested on everything from developing disease treatments to engineering drought-resistant crops to resurrecting genes of extinct species. The possibilities have expanded so rapidly that researchers, ethicists, and regulators have found themselves struggling to keep up.

God forbid that ‘ethicists’ (professional tellers of other people what to do) and regulators (professional tellers of other people what not to do) find themselves ‘struggling to keep up’.

Read it.

If you’ve ever wondered why some people can wake up before sunrise without an alarm while others struggle to get out of bed on time each morning, the answer lies in biology. Our circadian rhythm, also known as our internal body clock, largely influences our natural sleep-wake preferences, known as chronotypes.

That doesn’t mean your daily habits don’t matter. Light exposure, regular exercise, and consistent sleep schedules can also influence when you feel tired and when you wake up, our experts reveal. But for some people, rising early comes more naturally than it does for others. To better understand why some people are early risers—and whether night owls can shift their schedules—we asked sleep experts to explain the science behind it.

The Telegraph (UK).

Londoners have said they feel increasingly unsafe in the city, in a blow to Sir Sadiq Khan, the Mayor of London.

In a London School of Economics survey, 2,022 adults were asked whether living in the capital had become more or less safe generally. Some 54 per cent of respondents, made up of 61 per cent of women and 46 per cent of men, said they felt less safe than previously.

Only 22 per cent of men and 13 per cent of women said they felt London was safer.

We used to laugh at London for having someone named “Sadiq Khan” as Lord Mayer—and then Mamdani became mayor of New York….

The Telegraph (UK).

A biographer of Winston Churchill has accused the National Portrait Gallery of a “barefaced lie” over its claim that the wartime prime minister deliberately starved Indians.

Lord Roberts of Belgravia wrote to the gallery’s board on Monday to demand an explanation after The Telegraph exposed its claims that Churchill “wilfully” inflicted mass starvation on India during the Bengal famine of 1943.

The taxpayer-funded attraction recently installed a 40-minute-long film by Helen Cammock, an artist, whose voice-over narration claims that Churchill used mass starvation as a weapon of war.

The letter, signed by more than 50 peers, including Churchill’s grandson Lord Soames, has described the film as an “ideologically motivated rant”.

Proglodytes lie. It’s what they do.

The Telegraph (UK).

Pro-migrant campaigners boasted about how they had influenced a BBC children’s television show as part of an attempt to change Britain’s attitude towards asylum seekers, The Telegraph can reveal.

My, what a surprise.

The War Zone.

The saga of the Constellation class frigate is emblematic of so many chronic issues with the Navy’s way of procuring warships. The vessel that was supposed to make the wrongs of the Littoral Combat Ship debacle right failed spectacularly and the timing couldn’t have been worse. Now Constellation is dead and the Trump administration is building a different frigate from a different yard. While the Navy has said why it is moving on, we wanted the other side of the story. We recently had a conversation with George Moutafis, CEO of Fincantieri Marine Group, to get exactly that.

Before we get to the questions and answers, however, here is the backstory.

The U.S. Navy needed the Constellation class frigate, badly, and the program to construct it seemed built to deliver. Rather than a clean-sheet design, the service chose the proven Franco-Italian FREMM as its parent design, betting that adapting an existing platform would be far faster and cheaper, and overall less risky than starting from scratch.

It wasn’t. Among the issues plaguing the program, constant change orders pushed the design far from its origins. Two years into construction, the first ship was barely 10% complete while its design was still being finalized. Meanwhile, costs and schedules blew well past original projections.

As a result of these issues, the Navy late last year cancelled the program. That left Fincantieri’s Wisconsin yard sidelined while a contract to replace the Constellation class frigate went to rival Ingalls Shipbuilding in Pascagoula.

In the wake of the program’s implosion, the Navy created the Vessel Construction Manager (VCM) system. It uses a hired manager to hold the prime contract and run the show, overseeing shipyard performance, controlling subcontracts, and acting as a buffer between the service and the builder to keep costs and schedules on track.

In a wide-ranging, hour-long exclusive interview, Moutafis – appointed CEO on July 1, 2025 as the wheels were already falling off this project – gave us unique insights into Fincantieri’s version of how Constellation turned into a debacle and what needs to change as a result. He also touched on an array of other topics, which we will address in future installments.

Not the Bee.

I’m going to keep this brief.

Last night, there were two events happening to celebrate America. One was a cage match sponsored by Trump at the White House.

The other was a “Rise Up, Sing Out” event against “fascism” headlined by Jane Fonda, YouTuber Ms. Rachel, Julia Roberts, Robert De Niro, and Bette Midler. It was specifically scheduled to counter-program Trump’s UFC event.

You don’t need to know all the details. You only need the visuals, so here we go.

“They may have won all the battles/But we had all the good songs!” — Tom Lerer

Not the Bee.

Meet Kiana Sears:

The entitled we have always with us.