Researchers Use AI to Design Proteins That Block Snake Venom Toxins
15th November 2025
It has been a few years since AI began successfully tackling the challenge of predicting the three-dimensional structure of proteins, complex molecules that are essential for all life. Next-generation tools are now available, and the Nobel Prizes have been handed out. But people not involved in biology can be forgiven for asking whether any of it can actually make a difference.
A nice example of how the tools can be put to use is being released in Nature on Wednesday. A team that includes the University of Washington’s David Baker, who picked up his Nobel in Stockholm last month, used software tools to design completely new proteins that are able to inhibit some of the toxins in snake venom. While not entirely successful, the work shows how the new software tools can let researchers tackle challenges that would otherwise be difficult or impossible.