‘Molecular Library’ Opens Up New Frontier of Biological Space-Time
20th March 2025
“There are all kinds of proteins congregating at the cellular membrane, and if we want to understand what a protein does, how it’s regulated by its environment, and specifically how it triggers the spread of a disease, we need to understand what surrounds it,” explained Gupta, whose lab is part of the Nanobiology Institute at Yale’s West Campus.
Lacking the spatial nanotechnology required to understand the molecular context of how membrane proteins are regulated in health and diseases, the scholars developed a novel platform that provides access to around 2000 membrane proteins as well as a chemical tool to examine areas that surround proteins of interest.