Reprogrammed Cells Mix With Hybrid Scaffold to Rebuild Injured Muscle
22nd February 2021
In this new study, carried out by an international research team, the scientists have taken aim at what’s known at volumetric muscle loss, which can result from serious injuries such as those sustained in car crashes or tumor removal. This leaves the sufferer without much of the muscles’ natural ability to regenerate itself in the event of an injury, and current treatment options are limited.
The team set out to tackle this with the help of direct cell reprogramming, which entails turning one cell type into another without first returning it to an induced pluripotent state. This saw them enlist important structural cells in our connective tissue called fibroblasts, which were converted into induced myogenic progenitor cells (iMPCs) with the help of certain transcription factors.
We have the technology.