MIT Engineers Use Ultrasound for Improved Topical Drug Administration
19th September 2012
Ultrasound is likely most often associated with sonograms, but some MIT engineers are poised to change that. By using two separate beams of inaudible sound waves (one at low-frequency, the other high) the team were able to increase the permeability of skin, in a bid to improve the efficiency of transdermal drug delivery. The technique works thanks to the waves exciting bubbles in a fluid (such as water), forcing them to swell and move chaotically. Once the bubbles reach a certain size they implode, sucking the surrounding fluid into the void. This process creates micro-jets of liquid, which cause miniscule tears in the skin, allowing it to (painlessly) absorb chemicals more effectively. In practice, a pre-treated area of skin is then covered with a patch containing the correct dose of drugs — but don’t worry, the skin is said to grow back just a few hours later.
I can hardly wait.