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Study Reveals the Effects of Protein-Rich Diets on the Gut Microbiome and Overall Health

17th June 2024

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New research has shed light on the effects of protein-rich diets on the gut microbiome and overall health. Despite the increasing protein intake in Western diets, especially among athletes and individuals with obesity, the fate of undigested protein and its impact on human health remains largely unknown. A new study, presented at ASM Microbe, explores how excess undigested protein in the colon can be fermented to produce beneficial metabolites, such as short-chain fatty acids (SCFAs), or lead to the production of harmful metabolites like ammonia and sulfides, which are linked to gastrointestinal disorders and other health issues.

The research team conducted a series of experiments on mice, discovering that a switch to a protein-rich diet resulted in significant weight loss, reduced body fat and induced immediate changes to the gut microbiome. The study also compared different protein diets to examine the effects of individual amino acids on the gut microbiome’s composition and activity. Notably, the mice consuming aromatic amino-acid-rich proteins experienced the greatest weight and fat mass loss compared to those on standard protein and branched-chain amino-acid-rich protein diets.

UPDATE: 5 Best High-Protein Foods for Gut Health, According to Dietitians

 

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